If you have looked in the mirror lately and thought something looks a little flatter than it used to, you are not alone. From hip dips to the upper butt, from the outer thighs to the chest, rapid weight changes and GLP-1 medications can create a very specific type of volume loss. It is the kind that makes the body look suddenly deflated, even if the weight loss was intentional.

To understand what can actually be done to fix it and which treatments truly work, I went straight to the team at BeautyFix Medspa, one of the most respected names in advanced injectables and non surgical body contouring. Their team generously answered every question and provided a clear, honest breakdown of Alloclae, Radiesse and how these two treatments are changing the way we restore shape.
Below is everything you need to know, straight from their expertise.
WHAT EXACTLY IS ALLOCLAE?
BeautyFix describes Alloclae as an injectable fat transfer technology. It uses purified, bio enhanced fat to restore volume and contour in a soft, natural way. They explain it as the modern evolution of fat grafting. Traditional fat transfer requires surgery and often has unpredictable survival rates. Alloclae does the same job through an injectable format that is smoother, safer and extremely customizable. Put simply, Alloclae replaces fat with fat. It is ideal for anyone who wants fullness that looks like it has always been part of their own body.
WHAT IS RADIESSE?
Radiesse is completely different. It is a biostimulatory filler made of calcium hydroxylapatite. BeautyFix describes it as a product that builds a supportive scaffold under the skin. Radiesse restores structure, enhances firmness and encourages the body to produce collagen over time. Unlike Alloclae, Radiesse does not add fat. It reinforces the tissue and helps create lift and strength where the foundation has weakened.
ALLOCLAE VS. RADIESSE: HOW DO YOU CHOOSE?
BeautyFix provided the simplest and most helpful comparison. Alloclae equals fat based volume. Radiesse equals structural lift with collagen stimulation. If someone wants a soft, natural, believable fullness especially after weight loss, Alloclae is usually the choice. If someone needs more firmness, contour correction or deeper support under thin tissue, Radiesse may be the better fit.
HOW ALLOCLAE COMPARES TO TRADITIONAL FILLERS AND BBL
Traditional dermal fillers often use hyaluronic acid gel. BeautyFix does not use hyaluronic acid gel in the butt or hip area. They prefer Sculptra, Radiesse or Renuva because these products integrate more naturally and do not create a heavy gel appearance. A surgical BBL uses your own fat but requires anesthesia, liposuction and recovery. Alloclae bridges both worlds. It uses micronized fat in an injectable form. This is especially important for GLP-1 patients who often do not have enough body fat left to harvest for a traditional BBL.
WHY ALLOCLAE IS A FAVORITE FOR GLP-1 PATIENTS
BeautyFix sees very specific patterns of volume loss among GLP-1 users. They explained that most patients lose the underlying support structure first. This happens in the hips, hip dips, upper butt, outer thighs, arms and chest. Alloclae excels here because the treatment rebuilds the soft, natural padding that rapid weight loss takes away. The results look like the patient simply regained their natural shape. BeautyFix also noted that Alloclae has shown longer lasting results than many traditional fillers in studies so far.
WHAT AREAS RESPOND BEST TO ALLOCLAE?
According to BeautyFix, the top responding areas for volume restoration are: hips, hip dips, butt, thighs, breasts in women, and any area that looks deflated after rapid weight loss.
HOW MUCH PRODUCT DO PATIENTS TYPICALLY NEED?
The amount depends entirely on how much volume was lost. Hip dips and the butt usually require the greatest amount because these are the first areas to flatten. BeautyFix explained that for a noticeable difference, around 100 CCs may be appropriate, but every treatment is personalized to the person’s starting point and their goals.
WHAT IF THE PATIENT IS STILL LOSING WEIGHT?
BeautyFix emphasized that Alloclae is fat. If you continue to lose fat, you will metabolize the Alloclae as well. For long-lasting results, they recommend scheduling treatment during a stabilized weight period.
WHAT DOES “NO DOWNTIME” REALLY MEAN?
BeautyFix clarified that there is no surgical downtime associated with Alloclae. There is no bed rest, no restrictions on sitting or positioning and no lengthy recovery. Patients walk out immediately and return to daily activities the same day. The only limitations are avoiding workouts for 48 hours and allowing normal swelling to settle.
WHAT IS RECOVERY LIKE FOR GLP-1 PATIENTS?
GLP-1 patients often have thinner tissue, so they can feel slightly more tender than others. Expected downtime includes mild soreness, slight swelling and occasional bruising. BeautyFix said it is generally very smooth and minimal.
WHEN DO RESULTS SHOW?
Alloclae creates visible results immediately. Local anesthesia adds a bit of temporary swelling, but the true result appears after about 48 hours once the anesthetic fluid dissipates.
ARE THERE UNIQUE RISKS FOR GLP-1 PATIENTS?
BeautyFix said tissue quality is the biggest factor. GLP-1 patients often have less natural fat cushion. This makes injector experience essential. A skilled injector avoids overfilling and unevenness. Otherwise, risks mirror standard biostimulatory treatments.
WHAT ABOUT SAGGING OR CREASES UNDER THE BUTT?
Alloclae can help because fat and collagen provide better support. Radiesse is also very effective for tightening the small folds or creases under the butt. BeautyFix often combines treatments for the smoothest, most natural finish.
WHAT ABOUT PAIN OR ANESTHESIA?
There is no general anesthesia. Patients remain awake. BeautyFix uses local lidocaine to keep the area comfortable. According to their team, most patients rate the discomfort as a two or three out of ten.
THE TAKEAWAY
Alloclae and Radiesse are rewriting how we approach volume restoration. For anyone struggling with flattened, deflated or softened contours, particularly after GLP-1 weight loss, these treatments offer natural looking fullness, structure and shape without the need for surgery. All information in this article was generously provided by BeautyFix Medspa.
The information in this post reflects my personal research. It is not medical advice and should not replace consultation with a qualified, licensed provider. Any treatments referenced carry risks, and individual results will vary. Please speak with a medical professional before pursuing any aesthetic procedure.




